ANLIVA Hand Movement – standardizing care for patients with motor symptoms

January 29th, 2025

The ANLIVA™ Hand Movement application is being developed with the aim of aiding patients and physicians in monitoring and characterising symptoms of movement disorders such as Parkinsons’ disease (PD) and Essential Tremor (ET) using a simple smartphone.

Currently, motor symptoms of PD and ET are evaluated by physicians during clinical visits typically occurring a couple of times a year. But these evaluations are both time-consuming and subjective as well as only providing updates on a patient’s condition at the time of visit.

The vision behind the ANLIVA™ Hand Movement application is to use the high-quality sensors present in modern day smartphones to allow patients to record the movements of standard clinical tests at any time of their choosing. Patients can choose to perform tests used to evaluate e.g. kinetic tremor, postural tremor, rest tremor or bradykinesia. From the recorded sensor data, characteristic metrics of the movements are extracted which allow for the construction of objective measures of a patient’s movement disorder symptoms and provide a high resolution into the evolution of those symptoms. At the time of clinical visits, a physician can perform additional tests together with a patient and examine the history of results to gain a better understanding of the symptom progression. The objective and standardized aspects of the results together with the result history also provides benefits to interactions with new physicians. Finally, the ANLIVA™ Hand Movement application also aims at providing a standard measure of symptoms relevant for any pharmaceutical company running trials with motor symptoms as part of their targeted endpoints.

The ANLIVA™ Hand Movement application is currently undergoing clinical testing, and the aim is to file a 510(k) application with the FDA during 2025.

Quantification of movements, extraction of involuntary movements (top), construction of a distribution characterizing the involuntary movements (bottom).